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Dentistry proteomics: From laboratory development to clinical practice

Identifieur interne : 002C78 ( Main/Exploration ); précédent : 002C77; suivant : 002C79

Dentistry proteomics: From laboratory development to clinical practice

Auteurs : Taia M. B. Rezende [Brésil] ; Stella M. F. Lima [Brésil] ; Bernardo A. Petriz [Brésil] ; Osmar N. Silva [Brésil] ; Mirna S. Freire [Brésil] ; Octávio L. Franco [Brésil]

Source :

RBID : ISTEX:CD0177DD16AD839D089D5E38CF73AF133223A8ED

Descripteurs français

English descriptors

Abstract

Despite all the dental information acquired over centuries and the importance of proteome research, the cross‐link between these two areas only emerged around mid‐nineties. Proteomic tools can help dentistry in the identification of risk factors, early diagnosis, prevention, and systematic control that will promote the evolution of treatment in all dentistry specialties. This review mainly focuses on the evolution of dentistry in different specialties based on proteomic research and how these tools can improve knowledge in dentistry. The subjects covered are an overview of proteomics in dentistry, specific information on different fields in dentistry (dental structure, restorative dentistry, endodontics, periodontics, oral pathology, oral surgery, and orthodontics) and future directions. There are many new proteomic technologies that have never been used in dentistry studies and some dentistry areas that have never been explored by proteomic tools. It is expected that a greater integration of these areas will help to understand what is still unknown in oral health and disease. J. Cell. Physiol. 228: 2271–2284, 2013. © 2013 Wiley Periodicals, Inc.

Url:
DOI: 10.1002/jcp.24410


Affiliations:


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<term>Absolute quantitation</term>
<term>Acidic proteins</term>
<term>Bencharit</term>
<term>Better understanding</term>
<term>Biochem hubbard</term>
<term>Biol</term>
<term>Biomarker</term>
<term>Biomarkers</term>
<term>Bone marrow</term>
<term>Carbonic anhydrase</term>
<term>Carcinoma</term>
<term>Caries</term>
<term>Cell carcinoma</term>
<term>Cell proliferation</term>
<term>Cellular</term>
<term>Cellular physiology</term>
<term>Chang</term>
<term>Clusterin precursor</term>
<term>Cysteine</term>
<term>Cytoskeletal</term>
<term>Dehydrogenase</term>
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<term>Dental pulp</term>
<term>Dental structure</term>
<term>Dentin</term>
<term>Dentistry</term>
<term>Dentistry proteomic</term>
<term>Different types</term>
<term>Differentially</term>
<term>Early diagnosis</term>
<term>Edentulous patients</term>
<term>Eld</term>
<term>Electrospray ionization quadrupole</term>
<term>Ellias</term>
<term>Enamel</term>
<term>Enamel matrix</term>
<term>Enamel maturation</term>
<term>Enamel pellicle</term>
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<term>Endodontic infections</term>
<term>Endodontic treatment</term>
<term>Epithelial</term>
<term>Extracellular</term>
<term>Extracellular matrix</term>
<term>Follicle</term>
<term>Future directions</term>
<term>Gingival</term>
<term>Gingivalis</term>
<term>Healthy patients</term>
<term>Hubbard</term>
<term>Human saliva</term>
<term>Ionization</term>
<term>Isobaric tags</term>
<term>Itraq</term>
<term>Kinase</term>
<term>Laser</term>
<term>Ligament</term>
<term>Liquid spectrometry</term>
<term>Literature reports</term>
<term>Local relapse</term>
<term>Maldi</term>
<term>Mangum</term>
<term>Mass spectrometry</term>
<term>Matrix</term>
<term>Metabolic enzymes</term>
<term>Metabolism</term>
<term>Microbiol</term>
<term>Microorganism</term>
<term>Molecular mechanisms</term>
<term>Morsczeck</term>
<term>Mutans</term>
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<term>Novel proteins</term>
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<term>Oral pathol</term>
<term>Oral pathology</term>
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<term>Oscc</term>
<term>Osteogenic differentiation</term>
<term>Oxidative stress</term>
<term>Paes leme</term>
<term>Paracasei</term>
<term>Pathway</term>
<term>Pellicle</term>
<term>Pellicle formation</term>
<term>Peptide</term>
<term>Periodontal</term>
<term>Periodontal disease</term>
<term>Periodontal treatment</term>
<term>Periodontitis</term>
<term>Periodontol</term>
<term>Phosphoglycerate kinase</term>
<term>Phosphoglycerate mutase</term>
<term>Physiology</term>
<term>Porphyromonas gingivalis</term>
<term>Potential biomarkers</term>
<term>Precursor</term>
<term>Protein</term>
<term>Protein expression</term>
<term>Protein synthesis</term>
<term>Proteinase</term>
<term>Proteome</term>
<term>Proteomic</term>
<term>Proteomic analysis</term>
<term>Proteomic findings</term>
<term>Proteomic studies</term>
<term>Proteomic techniques</term>
<term>Proteomic tools</term>
<term>Proteomics</term>
<term>Pulp</term>
<term>Pulp cells</term>
<term>Pulp tissue</term>
<term>Pure titanium</term>
<term>Quadrupole mass analyzer</term>
<term>Quantitative proteomic analysis</term>
<term>Quantitative proteomics</term>
<term>Regeneration</term>
<term>Restorative dentistry</term>
<term>Rezende</term>
<term>Risk factors</term>
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<term>Salivary biomarkers</term>
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<term>Streptococcus</term>
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<term>Titanium</term>
<term>Trap mass spectrometer</term>
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<term>Uoride</term>
<term>Vimentin</term>
<term>Vitorino</term>
<term>Wang</term>
<term>Western blot</term>
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<term>Zhang</term>
<term>Zhou</term>
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<term>Acidic proteins</term>
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<term>Biol</term>
<term>Biomarker</term>
<term>Biomarkers</term>
<term>Bone marrow</term>
<term>Carbonic anhydrase</term>
<term>Carcinoma</term>
<term>Caries</term>
<term>Cell carcinoma</term>
<term>Cell proliferation</term>
<term>Cellular</term>
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<term>Chang</term>
<term>Clusterin precursor</term>
<term>Cysteine</term>
<term>Cytoskeletal</term>
<term>Dehydrogenase</term>
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<term>Dental pulp</term>
<term>Dental structure</term>
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<term>Dentistry</term>
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<term>Different types</term>
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<term>Early diagnosis</term>
<term>Edentulous patients</term>
<term>Eld</term>
<term>Electrospray ionization quadrupole</term>
<term>Ellias</term>
<term>Enamel</term>
<term>Enamel matrix</term>
<term>Enamel maturation</term>
<term>Enamel pellicle</term>
<term>Endodontic</term>
<term>Endodontic infections</term>
<term>Endodontic treatment</term>
<term>Epithelial</term>
<term>Extracellular</term>
<term>Extracellular matrix</term>
<term>Follicle</term>
<term>Future directions</term>
<term>Gingival</term>
<term>Gingivalis</term>
<term>Healthy patients</term>
<term>Hubbard</term>
<term>Human saliva</term>
<term>Ionization</term>
<term>Isobaric tags</term>
<term>Itraq</term>
<term>Kinase</term>
<term>Laser</term>
<term>Ligament</term>
<term>Liquid spectrometry</term>
<term>Literature reports</term>
<term>Local relapse</term>
<term>Maldi</term>
<term>Mangum</term>
<term>Mass spectrometry</term>
<term>Matrix</term>
<term>Metabolic enzymes</term>
<term>Metabolism</term>
<term>Microbiol</term>
<term>Microorganism</term>
<term>Molecular mechanisms</term>
<term>Morsczeck</term>
<term>Mutans</term>
<term>Myosin</term>
<term>Novel protein</term>
<term>Novel proteins</term>
<term>Odontoblast differentiation</term>
<term>Oral cavity</term>
<term>Oral lichen planus</term>
<term>Oral pathol</term>
<term>Oral pathology</term>
<term>Orthodontic treatment</term>
<term>Oscc</term>
<term>Osteogenic differentiation</term>
<term>Oxidative stress</term>
<term>Paes leme</term>
<term>Paracasei</term>
<term>Pathway</term>
<term>Pellicle</term>
<term>Pellicle formation</term>
<term>Peptide</term>
<term>Periodontal</term>
<term>Periodontal disease</term>
<term>Periodontal treatment</term>
<term>Periodontitis</term>
<term>Periodontol</term>
<term>Phosphoglycerate kinase</term>
<term>Phosphoglycerate mutase</term>
<term>Physiology</term>
<term>Porphyromonas gingivalis</term>
<term>Potential biomarkers</term>
<term>Precursor</term>
<term>Protein</term>
<term>Protein expression</term>
<term>Protein synthesis</term>
<term>Proteinase</term>
<term>Proteome</term>
<term>Proteomic</term>
<term>Proteomic analysis</term>
<term>Proteomic findings</term>
<term>Proteomic studies</term>
<term>Proteomic techniques</term>
<term>Proteomic tools</term>
<term>Proteomics</term>
<term>Pulp</term>
<term>Pulp cells</term>
<term>Pulp tissue</term>
<term>Pure titanium</term>
<term>Quadrupole mass analyzer</term>
<term>Quantitative proteomic analysis</term>
<term>Quantitative proteomics</term>
<term>Regeneration</term>
<term>Restorative dentistry</term>
<term>Rezende</term>
<term>Risk factors</term>
<term>Saliva</term>
<term>Saliva samples</term>
<term>Salivary</term>
<term>Salivary biomarkers</term>
<term>Salivary proteins</term>
<term>Serum albumin</term>
<term>Serum proteins</term>
<term>Siqueira</term>
<term>Spectrometry</term>
<term>Statherin</term>
<term>Streptococcus</term>
<term>Streptococcus mutans</term>
<term>Structural formation</term>
<term>Svensater</term>
<term>Titanium</term>
<term>Trap mass spectrometer</term>
<term>Unique proteins</term>
<term>Uoride</term>
<term>Vimentin</term>
<term>Vitorino</term>
<term>Wang</term>
<term>Western blot</term>
<term>Western blot approaches</term>
<term>Whole saliva</term>
<term>Wilkins</term>
<term>Zhang</term>
<term>Zhou</term>
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<front>
<div type="abstract" xml:lang="en">Despite all the dental information acquired over centuries and the importance of proteome research, the cross‐link between these two areas only emerged around mid‐nineties. Proteomic tools can help dentistry in the identification of risk factors, early diagnosis, prevention, and systematic control that will promote the evolution of treatment in all dentistry specialties. This review mainly focuses on the evolution of dentistry in different specialties based on proteomic research and how these tools can improve knowledge in dentistry. The subjects covered are an overview of proteomics in dentistry, specific information on different fields in dentistry (dental structure, restorative dentistry, endodontics, periodontics, oral pathology, oral surgery, and orthodontics) and future directions. There are many new proteomic technologies that have never been used in dentistry studies and some dentistry areas that have never been explored by proteomic tools. It is expected that a greater integration of these areas will help to understand what is still unknown in oral health and disease. J. Cell. Physiol. 228: 2271–2284, 2013. © 2013 Wiley Periodicals, Inc.</div>
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